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Introduction: Potassium-competitive acid blockers are effective against proton pump inhibitor-refractory gastroesophageal reflux disease; however, their long-term use is associated with economic disadvantages. Endoscopic procedures may reduce potassium-competitive acid blocker use. This study aimed to determine the optimal treatment strategy for patients with proton pump inhibitor-refractory gastroesophageal reflux disease from a cost-effectiveness perspective.
View Article and Find Full Text PDFManagement of Patients With Refractory Reflux-Like Symptoms Despite Proton Pump Inhibitor Therapy: Evidence-Based Consensus Statements.
Aliment Pharmacol Ther
December 2024
Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, and Kansas City VA Medical Center, Kansas City, Missouri, USA.
Background: Many patients diagnosed with gastro-oesophageal reflux disease (GERD) have persistent symptoms despite proton pump inhibitor (PPI) therapy.
Aims: The aim of this consensus is to provide evidence-based statements to guide clinicians caring for patients with refractory reflux-like symptoms (rRLS) or refractory GERD.
Methods: This consensus was developed by the International Working Group for the Classification of Oesophagitis.
Efficacy and Safety of Anti-Reflux Mucosectomy versus Radiofrequency Ablation of the Lower Esophageal Sphincter for the Treatment of Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis.
Gastrointest Endosc
December 2024
Department of Surgery, Hospital Alemán of Buenos Aires, Argentina.
Background And Aims: Gastroesophageal reflux disease (GERD) affects 10-30% of the population. Endoscopic anti-reflux therapies have been proposed for carefully selected patients. The aim of this study was to compare outcomes between endoscopic anti-reflux mucosectomy (ARMS) and endoscopic radiofrequency ablation of the lower esophageal sphincter (Stretta procedure) for the treatment of GERD.
View Article and Find Full Text PDFA retrospective review of infant-inducible laryngeal obstruction a subtype of paradoxical vocal fold motion: Evaluation and management.
Am J Otolaryngol
November 2024
Surgery, Division of Otolaryngology, University of New Mexico Hospital, Albuquerque, NM, USA. Electronic address:
Introduction: There is a paucity of literature on pre-adolescent paradoxical vocal fold motion (PVFM), PVFM is a sub-type of inducible laryngeal obstruction. Studies typically focus on older patients, however the discovery of this entity in pre-adolescent pediatric patients has led to more questions about how this entity manifests differently and is treated differently in younger populations. Initially considered psychosomatic and commonly mistaken for asthma, PVFM etiology is now thought to be associated underlying neurologic conditions and may have irritant triggers with proposed mechanisms related to laryngeal hypersensitivity.
View Article and Find Full Text PDFComputed tomography roadmap for post-operative fundoplication imaging with a novel structured reporting checklist.
J Minim Access Surg
November 2024
Department of Radiology, Delta Imaging, Zen Multispeciality Hospital, Mumbai, Maharashtra, India.
Introduction: With increasing numbers and acceptability of laparoscopic anti-reflux surgery (LARS) procedures over long-term medical treatment in the past decade, it follows that the complications of fundoplication wrap are seen intermittently with recurrent symptoms of heartburn and dysphagia. Endoscopy and barium swallow are the initial investigations performed for suspected fundoplication wrap failures. However, with easy availability of multislice computed tomography (CT) and the multiplanar reconstructions along with reduction in familiarity with barium examinations, it would be prudent for the surgeons to familiarise themselves with various appearances of wrap failure.
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