A woman, fitted with a Mirena intrauterine system (IUS), presented with a positive pregnancy test and a 5-day history of per vaginam bleeding and left iliac fossa pain. Beta-hCG level was raised at 1815 IU/l and a pelvic ultrasound scan showed a normal empty uterus. An abdominal x-ray showed that the IUS was in the left hypochondrium. At laparoscopy, an ectopic pregnancy was discovered in the left fallopian tube. The IUS was removed laparoscopically. This is likely to be the first reported case of a simultaneous ectopic pregnancy and an extrauterine system. It is not clear whether removal of the Mirena IUS was necessary.
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http://dx.doi.org/10.1783/147118902101196036 | DOI Listing |
BJOG
January 2025
Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Objective: To determine the diagnostic performance and clinical utility of the M4 prediction model and the NICE algorithm managing women with pregnancy of unknown location (PUL).
Design: The study has a superiority design regarding specificity for non-ectopic pregnancy for M4, given that the primary outcome of sensitivity for ectopic pregnancy (EP) is non-inferior in comparison with the NICE algorithm.
Setting: Emergency gynaecology units in Sweden.
Cureus
December 2024
Emergency, Ras Tanura General Hospital, Eastern Health Cluster, Ministry of Health, Ras Tanura, SAU.
This case highlights the critical role of early radiological screening by ultrasound in identifying uterine anomalies. In this report, we discuss a 39-year-old pregnant woman, gravida 4 para 3, and her fetus at gestational age 18 weeks. The patient was referred to the Obstetrics and Gynecology Emergency Department at Qatif Central Hospital, Saudi Arabia, from a private hospital due to an ultrasound study indicating a possible ectopic pregnancy with an abdominal fetal location.
View Article and Find Full Text PDFCureus
December 2024
Department of Obstetrics and Gynecology, School of Health Sciences, University of Patras, Patras, GRC.
Heterotopic pregnancy is defined as the simultaneous presence of an intrauterine and an extrauterine pregnancy and is considered a rare condition. As a part of this entity, heterotopic triplet pregnancy, defined as the presence of three embryos, with at least one being ectopic, is exceedingly rare. In recent years, the broad use of assisted reproductive techniques to help infertile couples has contributed to the constant rise of non-spontaneous heterotopic triplets.
View Article and Find Full Text PDFFront Cardiovasc Med
January 2025
Department of Intensive Care Medicine, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, China.
A young female patient suffered cardiogenic shock after undergoing surgery for an ectopic pregnancy. Coronary artery computed tomography angiography (CTA) revealed a left main artery (LM) originating from the right coronary sinus and traveling between the aorta and pulmonary artery. We successfully resuscitated the patient with mechanical circulatory support using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and an intra-aortic balloon pump (IABP).
View Article and Find Full Text PDFBiomater Sci
January 2025
Department of Gynecology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510655, China.
Currently, hormonal therapy for endometriosis faces challenges in achieving a balance between treatment and preserving the chance of pregnancy. Therefore, the development of non-hormonal therapy holds significant clinical importance. Angiogenesis is a hallmark of endometriosis, and anti-angiogenic therapies targeting the hypoxia-inducible factor-1α (HIF-1α) pathway are considered potential approaches for endometriosis.
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