On the first day and 3-10 or 40-60 days after a single whole-body gamma-irradiation with doses of 0.25, 0.5 and 1 Gy, the pubertal female Wistar rats coupled with intact males. The embryogenesis and early postnatal ontogenesis of posterity of two generations from these parents were investigated. A raised mutation rate and physiological inferiority of the progeny was found, depending both on a dose and on the degree of oocyte maturity at the moment of the irradiation. The obtained data showed the instability of the irradiated genome in a number of generations.

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