AI Article Synopsis
- A 2-year-old girl with Crigler-Najjar syndrome type I exhibited severe cerebellar symptoms, which are unusual for her age group.
- The symptoms indicated the presence of bilirubin encephalopathy, a condition related to high bilirubin levels that can affect neurological function.
- Her condition improved gradually with phototherapy, highlighting that cerebellar symptoms might be an early sign of kernicterus in children with this syndrome.
Article Abstract
Children with Crigler-Najjar syndrome type I are at increased risk for neurologic deficits. Cerebellar symptoms are not prominent and appear in adolescent or adult patients with this syndrome. We report a 2-year-old female with Crigler-Najjar syndrome type I who presented severe cerebellar symptoms revealing bilirubin encephalopathy. The patient improved slowly with the duration of phototherapy. Cerebellar symptoms can be the initial manifestation of kernicterus in children with Crigler-Najjar syndrome type I.
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| http://dx.doi.org/10.1016/s0887-8994(02)00425-3 | DOI Listing |
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