[Application of phage antibody library technology: problems and their solutions].

Di Yi Jun Yi Da Xue Xue Bao

Laboratory of Tropical Diseases, Department of Tropical Medicine, First Military Medical University, Guangzhou 510515, China.

Published: April 2002

AI Article Synopsis

  • Phage antibody library technology is widely used for engineering antibodies but faces challenges in key processes like library construction and screening.
  • The authors analyze these issues to understand their impacts on antibody development.
  • They propose solutions to improve the efficiency and effectiveness of these critical steps in antibody engineering.

Article Abstract

In spite of the wide application of phage antibody library technology in antibody engineering, problems are often present especially in the key steps, for instance, library construction, screening and expression of the antibody. The authors conducted an analysis of these problems and thereby proposes their solutions.

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