Objective: To evaluate the diagnostic value of superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging (MRI) for hepatic focal solid lesions.
Methods: SPIO (Feridex)-enhanced MRI examination was performed in 28 cases of hepatic space-occupying lesions defined by CT or MRI or other methods. In post-contrast enhanced examination, the signal intensity and contrast-to-noise ratio (CNR) were measured in lesions and normal hepatic parenchyma in T2-weighted images (T2WI) and were compared with those in pre-contrast enhanced MRI. The number and morphology of the lesions were visualized for qualitative diagnostic analysis.
Results: In Feridex-enhanced MRI, the signal intensity of normal hepatic parenchyma was decreased while the CNR between lesions and normal liver tissues significantly improved in comparison with that in pre-contrast enhanced examination.
Conclusion: Feridex-enhanced T2WI examination significantly improves detection of hepatic lesions and is valuable in diagnosing hepatic focal solid lesions.
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