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[Modest clinical benefits of ASAT analysis in today's health care. A case report of macro-ASAT giving rise to pathologically increased ASAT levels]. | LitMetric

[Modest clinical benefits of ASAT analysis in today's health care. A case report of macro-ASAT giving rise to pathologically increased ASAT levels].

Lakartidningen

Avdelningen för klinisk kemi och farmakologi, Akademiska sjukhuset, Uppsala.

Published: September 2002

Aspartate aminotransferase (AST) may occur as a macroenzyme after forming a complex with immunoglobulins. The complex results in decreased plasma clearance and thus elevated AST levels. So far, macro-AST has only been described in a few patients. Here, we report a case of macro-AST in a healthy female. Clinicians should be aware of this phenomenon so that patients are not subjected to unnecessary investigations.

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