Study Objective: To estimate the association between preoperative beta-human chorionic gonadotropin (hCG) and progesterone levels, and success of linear salpingostomy in treatment of tubal pregnancy.

Design: Retrospective case control study (Canadian Task Force classification II-1).

Setting: Women's general hospital.

Patients: Three hundred five women undergoing laparoscopic linear salpingostomy for ectopic pregnancy.

Intervention: Examination of risk factors for surgical failure of salpingostomy by analyzing corresponding receiver operating curves.

Measurements And Main Results: In 305 women, intervention was successful in 272 and failed in 33, as assessed by either postoperative hemorrhage (16) or rising beta-hCG values (14); 3 women had both. Of 295 patients in whom beta-hCG was evaluated preoperatively, 149 (50.5%) had values of 1000 mU/ml. or less; 75% had progesterone levels of 10 ng/ml or below. No association was found between preoperative beta-hCG and progesterone levels and the success of linear salpingostomy.

Conclusion: Preoperative beta-hCG and progesterone levels are of no significance with regard to success of linear salpingostomy for treatment of tubal pregnancy.

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http://dx.doi.org/10.1016/s1074-3804(05)60519-1DOI Listing

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