A clinical isolate of Pseudomonas aeruginosa was found to produce a clavulanic acid-inhibited extended-spectrum beta-lactamase with a pI of 6.4. PCR, cloning, and sequencing experiments showed that the corresponding bla(TEM-21) gene was part of a chromosomally located Tn801 transposon disrupted by an IS6100 element and adjacent to an aac(3)-II gene.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128703 | PMC |
| http://dx.doi.org/10.1128/AAC.46.11.3624-3626.2002 | DOI Listing |
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