Background: A conceptual model implicitly or explicitly guides research. Some researchers identify the conceptual model prior to conducting their studies. Other researchers may eventually come upon a conceptual model that provides a context for the research already completed and direction for future studies.
Aim: The purpose of this article is to explain how one researcher, working with a theoretician, found a conceptual model that has provided a frame of reference for her past, present, and future studies and has allowed her to view her heretofore somewhat disparate studies as a more coherent programme of research.
Conclusion: Finding an explicit conceptual model provided a meaningful frame of reference for interpreting previous research. Finding an explicit model also had the benefit of uncovering of new possibilities for research. In particular, as the findings from previous research were brought together within the context of the conceptual model, unanticipated areas of future study were identified.
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http://dx.doi.org/10.1046/j.1365-2648.2002.02377.x | DOI Listing |
BMC Public Health
January 2025
Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA.
Background: Understanding the risk factors of hypertension among women of reproductive age (18-44 years) is important for guiding health programs aimed at reducing the burden of hypertensive disorders in this population. Therefore, the objective of this study was to investigate predictors of self-reported hypertension among women of reproductive age in North Dakota.
Methods: Behavioral Risk Factor Surveillance System data for the years 2017, 2019, and 2021 were obtained from North Dakota Department of Health and Human Services.
Pharmacoeconomics
January 2025
Sheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, The University of Sheffield, Regent Court, 30 Regent Street, Sheffield, UK.
Background: Testing high-risk populations for non-visible haematuria may enable earlier detection of bladder cancer, potentially decreasing mortality. This research aimed to assess the cost-effectiveness of urine dipstick screening for bladder cancer in high-risk populations in England.
Methods: A microsimulation model developed in R software was calibrated to national incidence data by age, sex and stage, and validated against mortality data.
J Nucl Med
January 2025
Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts;
Radionuclides used for imaging and therapy can show high molecular specificity in the body with appropriate targeting ligands. We hypothesized that local energy delivered by molecularly targeted radionuclides could chemically activate prodrugs at disease sites while avoiding activation in off-target sites of toxicity. As proof of principle, we tested whether this strategy of radionuclide-induced drug engagement for release (RAiDER) could locally deliver combined radiation and chemotherapy to maximize tumor cytotoxicity while minimizing off-target exposure to activated chemotherapy.
View Article and Find Full Text PDFComput Biol Med
January 2025
Department of Mathematics, NED University of Engineering & Technology, Pakistan. Electronic address:
For consideration of uncertainties of a medicine dataset, a new conceptual architecture fuzzy three-valued logic is introduced in this research work. The proposed concept is applied to the heart disease dataset for the assessment of heart disease risk in individuals. By comparison of three binary (0,1) input variables, the variables' uncertainties and their collective impact can be analyzed that provide complete information leading to better outcome prediction.
View Article and Find Full Text PDFAcad Med
December 2024
R.H. Kon is associate professor of medicine, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia; ORCID: https://orcid.org/0000-0002-3326-5203.
ProblemLongitudinal patient relationships can positively affect medical students' professional identity formation (PIF), understanding of illness, and socialization within medical practice, but a longitudinal integrated clerkship (LIC) model is not always feasible. The authors describe the novel Patient Student Partnership (PSP) program, which provides authentic roles for students in mentored longitudinal patient relationships while maintaining a traditional block clerkship model.ApproachThe PSP program at the University of Virginia School of Medicine pairs all matriculating medical students with a patient living with chronic illness to follow across multiple health care settings until graduation.
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