Dose measurements in brachytherapy 192Ir implants are often difficult due to large dose gradients and complex photon spectra. Therefore, tissue-equivalent detectors with a high spatial resolution, such as the highly promising LiF:Mg,Cu,P thermoluminescent detectors (TLDs) are required. It was the aim of the present work to ascertain if miniature LiF:Mg,Cu,P TLDs can effectively measure the dose distribution around 192Ir implants. 'Pin worm' TLDs (type MCP, diameter 0.6 mm, length 2 mm) were compared with GR-200R (SSDL, Beijing) rods cut in half. The TLDs were tested for reproducibility and energy dependence using high dose rate (HDR) and low dose rate (LDR) brachytherapy units. 192Ir measurements were performed in a tissue equivalent phantom accommodating hollow needles and catheters routinely used in brachytherapy. Pin worms had an average reproducibility of less than +/-2% (1 SD) and a detection limit of less than 10 microGy. The small dimensions of the pin worms allowed their placement within brachytherapy needles and catheters. The measured relative dose distribution was in good agreement with the predictions of a computerised treatment planning system (ADAC Pinnacle); however, limitations in the TLD energy correction did not allow for absolute dose comparison.
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http://dx.doi.org/10.1093/oxfordjournals.rpd.a006012 | DOI Listing |
Phys Imaging Radiat Oncol
October 2024
Division of Medical Physics, Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK), Partner Site DKTK, Freiburg, Germany.
J Contemp Brachytherapy
June 2024
Department of Medical Physics, German Oncology Center, University Hospital of the European University, Limassol, Cyprus.
Purpose: The aim of this study was a retrospective dosimetric comparison of iridium-192 (Ir) high-dose-rate (HDR) interstitial brachytherapy plans using model-based dose calculation algorithm (MBDCA) following TG-186 recommendations and TG-43 dosimetry protocol for breast, head-and-neck, and lung patient cohorts, with various treatment concepts and prescriptions.
Material And Methods: In this study, 59 interstitial Ir HDR brachytherapy cases treated in our center (22 breast, 22 head and neck, and 15 lung) were retrospectively selected and re-calculated with TG-43 dosimetry protocol as well as with Acuros BV dose calculation algorithm, with dose to medium option based on computed tomography images. Treatment planning dose volume parameter differences were determined and their significance was assessed.
Oral Radiol
April 2024
Department of Oral and Maxillofacial Radiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
Objectives: Low-dose-rate brachytherapy (LDR-BT) with Au grains and Ir pins is an essential treatment option for oral cancer due to its high rate of local control and low invasiveness. However, the radiation exposure of medical radiation workers is concerning. Thus, we aimed to determine the radiation dose delivered to medical radiation workers during LDR-BT using Au grains and Ir pins for oral cancer.
View Article and Find Full Text PDFBrachytherapy
November 2023
Department of Radiation Oncology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju-si, Gangwon-do, Republic of Korea. Electronic address:
Purpose: The current protocol for use of the image-guided adaptive brachytherapy (IGABT) procedure entails transport of a patient between the treatment room and the 3-D tomographic imaging room after implantation of the applicators in the body, which movement can cause position displacement of the applicator. Moreover, it is not possible to track 3-D radioactive source movement inside the body, even though there can be significant inter- and intra-fractional patient-setup changes. In this paper, therefore, we propose an online single-photon emission computed tomography (SPECT) imaging technique with a combined C-arm fluoroscopy X-ray system and attachable parallel-hole collimator for internal radioactive source tracking of every source position in the applicator.
View Article and Find Full Text PDFJ Contemp Brachytherapy
April 2023
Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Purpose: Manufacturing of miniaturized high activity iridium-192 (Ir) sources have been made a market preference in modern brachytherapy. Smaller dimensions of the sources are flexible for smaller diameter of the applicators, and it is also suitable for interstitial implants. Presently, cobalt-60 (Co) sources have been commercialized as an alternative to Ir sources for high-dose-rate (HDR) brachytherapy, since Co source have an advantage of longer half-life comparing with Ir source.
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