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http://dx.doi.org/10.1006/jtbi.2002.3074 | DOI Listing |
Plant Physiol
December 2024
Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Northeast Region), Ministry of Agriculture and Rural Affairs/Northeast Agricultural University, Harbin, 150030, China.
Pumpkin (Cucurbita maxima D.) is typically monoecious with individual male and female flowers, and its yield is associated with the degree of femaleness, i.e.
View Article and Find Full Text PDFNat Commun
November 2024
Department of Algal Development and Evolution, Max Planck Institute for Biology Tübingen, Tübingen, Germany.
Nuclear three dimensional (3D) folding of chromatin structure has been linked to gene expression regulation and correct developmental programs, but little is known about the 3D architecture of sex chromosomes within the nucleus, and how that impacts their role in sex determination. Here, we determine the sex-specific 3D organization of the model brown alga Ectocarpus chromosomes at 2 kb resolution, by mapping long-range chromosomal interactions using Hi-C coupled with Oxford Nanopore long reads. We report that Ectocarpus interphase chromatin exhibits a non-Rabl conformation, with strong contacts among telomeres and among centromeres, which feature centromere-specific LTR retrotransposons.
View Article and Find Full Text PDFGene
January 2025
School of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, WITS 2050 Johannesburg, South Africa. Electronic address:
The genetic basis of somatic cell identity in avian sex determination is still unknown. FET1, an endogenous retrovirus, has previously been demonstrated to be expressed during gonad development. Here, we report expression of FET1 related transcripts in non-gonadal tissue during chicken development.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2024
Max Planck Institute for Biology, Tübingen 72076, Germany.
Most eukaryotes have one nucleus and nuclear genome per cell. Ciliates have instead evolved distinct nuclei that coexist in each cell: a silent germline vs. transcriptionally active somatic nuclei.
View Article and Find Full Text PDFInt J Immunopathol Pharmacol
August 2024
Clinical Pathology Department, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Objectives: Human endogenous retroviruses (HERVs) are integral components of the human genome, and their reactivation has been implicated in the pathogenesis of some malignancies. External viral co-infections are suspected to play a role in HERV transactivation. This study aimed to investigate the expression of HERV-K np9 elements and HERV-R env gene in pediatric acute lymphoblastic leukemia (ALL) patients.
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