Structural characteristics of mixed salivary pools were studied in 20 subjects aged 16-18 years. The examinees were divided into 2 groups, 10 subjects per group. Group 1 included patients with negligible caries involvement (CDL index 3.0 +/- 0.62), group 2 consisted of patients with greater involvement (CDL index 10.1 +/- 0.62). Statistically significant differences between these groups were detected for 2 parameters: pH and optical density. Acidification of the saliva and its optical density were higher in patients with greater caries involvement. Structural characteristics of the saliva were disordered in patients with multiple caries, which indicated impairment of mechanisms maintaining Ca2+ and HPO4(2-) ions in an oversaturated state and a decrease in the mineralizing potential of oral fluid. These data can be used for explaining the molecular mechanisms of homeostasis disorders in the oral cavity and evaluating the efficiency of preventive and therapeutic measures at early stages of dental caries.
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