Preoperative prediction of early mortality and morbidity in coronary bypass surgery.

Cardiovasc Surg

Heartcenter, Department of Thoracic and Cardiac Surgery-414, University of Nijmegen Medical Center, St. Radboud, PO Box 9101, The Netherlands.

Published: October 2002

AI Article Synopsis

  • Developed a scoring system to predict early mortality and morbidity in patients undergoing CABG surgery, distinguishing between low and high-risk individuals.
  • Used data from 563 patients for development and 969 for validation, with logistic regression analysis identifying key risk factors.
  • Found that specific factors like age, gender, and existing health conditions significantly influenced early mortality (1.8% low risk vs. 13.4% high risk) and morbidity (17% low risk vs. 41% high risk), demonstrating the system's effectiveness with ROC areas of 0.81 and 0.73, respectively.

Article Abstract

Objective: A scoring system to predict early mortality and morbidity in CABG, distinguishing low and high risk patients.

Methods: 563 patients (1998) served as development dataset, 969 patients as validation set. Univariate and logistic regression analysis was used to identify risk factors.

Results: Gender, hypertension, pulmonary disease, reoperation, age, operative status and left-ventricular function were predictive variables for early mortality. The area under the ROC curve was 0.81. We identified a low risk, mortality of 1.8% and a high-risk group, mortality of 13.4%. Diabetes, hypertension, kidney and lung disease, reoperation, operative status and left ventricular function were predictive variables for morbidity. The area under the ROC curve was 0.73. We identified a low risk, morbidity of 17%, and a high-risk group, morbidity of 41%.

Conclusion: This scoring system is a simple system identifying a low and high-risk group for morbidity and early mortality.

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Source
http://dx.doi.org/10.1016/s0967-2109(02)00081-9DOI Listing

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