A new Salmonella enterica serovar Typhimurium strain has been constructed to facilitate tightly regulated gene expression. Arabinose-inducible and glucose-repressible expression of a T7 RNA polymerase gene that has been integrated with an adjacent araC-P(BAD) control element into the bacterial chromosome allows dynamic control of T7 promoter-driven RNA transcription.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC135372 | PMC |
http://dx.doi.org/10.1128/JB.184.21.6056-6059.2002 | DOI Listing |
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