Synthesis and evaluation of 5-HT(2A) and 5-HT(2C) receptor binding affinities of novel pyrimidine derivatives.

Bioorg Med Chem Lett

Chemical Research Department, EGIS Pharmaceuticals Ltd., PO Box 100, 1475, Budapest, Hungary.

Published: November 2002

In an effort to find potential anxiolytic and/or antipsychotic agents with selective 5-HT(2C) affinity a series of new pyrimidine derivatives was prepared and the binding affinities for 5-HT(2A) and 5-HT(2C) receptors were determined.

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http://dx.doi.org/10.1016/s0960-894x(02)00660-1DOI Listing

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