[Pro- and antioxidant system activity in cervical mucosa].

Ginekol Pol

Zakładu Genetyki Człowieka PAN w Poznaniu.

Published: July 2002

AI Article Synopsis

  • The study aimed to assess the activity of antioxidant and pro-oxidant systems in cervical mucus of both healthy women and those with cervical disorders.
  • After liquefying cervical mucus, researchers measured the activity of specific enzymes using chemiluminescence assays.
  • Results indicated that healthy women's cervical mucus had higher antioxidant activity, while women with dysplasia showed increased levels of xanthine oxidase, highlighting the mucus's protective role for cervical cells and sperm.

Article Abstract

The aim of the study was to evaluate the activity of the pro- and antioxidant systems in cervical mucus of healthy women and women with pathological of disorders cervical. After cervical mucus liquefaction, the activity of superoxide dismutase, catalase and xanthine oxidase was determined by means of chemiluminescence assays. The activity of the antioxidant system in cervical mucus of healthy women was higher as compared to the group with pathological cervical disorders. Moreover, in mucus samples obtained from women with dysplasia, the significantly heightened activity of xanthine oxidase (strong pro-oxidant) was observed. The antioxidant system present in cervical mucus may protect both the cells of the uterine cervix and the viable sperm.

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