An improved synthesis of the antiulcer drug Ranitidine from an oxazolidine derivative is reported.

Download full-text PDF

Source

Publication Analysis

Top Keywords

method synthesis
4
synthesis ranitidine
4
ranitidine improved
4
improved synthesis
4
synthesis antiulcer
4
antiulcer drug
4
drug ranitidine
4
ranitidine oxazolidine
4
oxazolidine derivative
4
derivative reported
4

Similar Publications

MXenes are a class of 2D transition metal carbides and nitrides (MXT) that have attracted significant interest owing to their remarkable potential in various fields. The unique combination of their excellent electromagnetic, optical, mechanical, and physical properties have extended their applications to the biological realm as well. In particular, their ultra-thin layered structure holds specific promise for diverse biomedical applications.

View Article and Find Full Text PDF

Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival.

Front Oncol

January 2025

Gynecologic Oncology Section, Stephenson Cancer Center, Obstetrics and Gynecology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

Background/objectives: Patients with ovarian cancer commonly experience metastases and recurrences, which contribute to high mortality. Our objective was to better understand ovarian cancer metastasis and identify candidate biomarkers and drug targets for predicting and preventing ovarian cancer recurrence.

Methods: Transcripts of 770 cancer-associated genes were compared in cells collected from ascitic fluid versus resected tumors of an ES-2 orthotopic ovarian cancer mouse model.

View Article and Find Full Text PDF

Background And Objective: Primary hyperoxaluria (PH), a rare autosomal recessive disorder, results in defective metabolism of oxalate, leading to increased oxalate levels. is a nonpathological anaerobic bacterium that uses oxalate for its survival and thus decreases the plasma oxalate levels. We aimed to use randomized controlled trials (RCTs) to evaluate the efficacy of in treating PH.

View Article and Find Full Text PDF

Two-dimensional (2D) hybrid materials, particularly those based on boron nitride (BN) and graphene oxide (GO), have attracted significant attention for energy applications owing to their distinct structural and electronic properties. BN/GO composites uniquely combine the mechanical strength, thermal stability and electrical insulation of BN with the high conductivity and flexibility of GO, creating advanced materials ideal for the fabrication of batteries, supercapacitors and fuel cells. These hybrids offer synergistic effects, enhanced charge transport, increased surface area, and improved chemical stability, making them promising candidates for high-performance energy systems.

View Article and Find Full Text PDF

Biocatalytic Strategies for Nitration Reactions.

JACS Au

January 2025

Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy, Qingdao New Energy Shandong Laboratory, CAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.

Nitro compounds are key synthetic intermediates used as enabling tools in synthesis and found in a large range of essential compounds, including pharmaceuticals, pesticides, and various organic dyes. Despite recent methodological developments, the industrial preparation of nitro compounds still suffers from harsh reaction conditions, along with poor selectivity and a problematic environmental footprint. Although biological enzymatic methods exist, mild approaches for bionitration are still underexplored.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!