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Ex Vivo Fluorescence Confocal Microscopy Meets Innovation and Revolutionary Technology, for "Real-Time" Histological Evaluation, in Pediatric Surgical Oncology.
Children (Basel)
November 2024
Pediatric Surgery Unit, Salesi Children's Hospital, Polytechnic University of Marche, Via Filippo Corridoni, 16, 60123 Ancona, Italy.
Background And Aim: Ex vivo fluorescence confocal microscopy (FCM) systems are innovative optical imaging tools that create virtual high-resolution histological images without any standard tissue processing, either freezing or fixing in formalin and embedding in paraffin. These systems have opened an era that would revolutionize pathological examination by providing rapid, real-time assessments across various pathology subspecialties, potentially replacing conventional methods that are tissue- and time-consuming. This study aimed to present the first utilization of FCM in pediatric surgical oncology, focusing on assessing the benefits, particularly in facilitating rapid and accurate diagnosis.
View Article and Find Full Text PDFNEVI IN CHILDREN: CLINICO-DERMOSCOPIC CONCEPTS ASSOCIATED WITH LOCATION.
Georgian Med News
October 2024
European University, Department of Dermatology, Tbilisi, Georgia.
Unlabelled: Nevi developed in children are one of the topical issues of pediatric dermatology. The constant change in size and shape often worries parents, and unnecessary removal of the nevi is planned. The development of accompanying scars and sometimes recurring nevi presents a new problem for parents and dermatologists.
View Article and Find Full Text PDFArticle Synopsis
- Spitz nevus is a rare benign tumor and this study examined its characteristics among Iranian patients from 2016-2021, focusing on demographics and histopathology.
- A total of 86 patients were studied, with a mean age of 15.6 years, and the most common locations were the upper extremities and face; most patients had disease durations of 1-2 years.
- The histopathological analysis showed different types of Spitz nevus, emphasizing the importance of further research in improving diagnostic methods.
Benign Nevi Mimicking Melanoma: A Diagnostic Dilemma.
Cureus
November 2024
Medicine, Batterjee Medical College, Jeddah, SAU.
Article Synopsis
- * Misdiagnosis (both under and over) of melanomas occurs frequently because benign lesions can mimic melanoma characteristics.
- * Accurate diagnosis relies on strong clinico-pathological correlation, detailed cytological analysis, and appropriate use of immunohistochemistry to prevent harmful misdiagnoses.
Regressing Eruptive Disseminated Spitz Nevi: A Case Report.
Cureus
October 2024
Dermatology, The Third People's Hospital of Hangzhou, Hangzhou, CHN.
Article Synopsis
- Eruptive disseminated Spitz nevi (EDSNs) are rare skin growths that typically do not become cancerous and most often maintain their appearance, leading to psychological stress for those affected.
- An 18-year-old male experienced a sudden increase in pigmented nevi over a period of 20 days.
- After a two-year observation period, most of these nevi disappeared on their own without any medical intervention.
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