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Incremental hemodialysis transition in veterans and nonveterans with kidney failure.
Curr Opin Nephrol Hypertens
January 2025
Division of Nephrology, Hypertension, and Kidney Transplantation, Lundquist Institute at Harbor-UCLA Medical Center, Torrance.
Purpose Of Review: Initiation of hemodialysis treatment with a thrice-weekly prescription is currently the standard of care irrespective of patients' residual kidney function (RKF), comorbidities, and preferences.
Recent Findings: Each year ∼12 000 Veterans with advanced kidney disease progress to end-stage kidney disease (ESKD) requiring dialysis and comprise greater than 10% of the US incident ESKD population. Dialysis is costly and is associated with impaired health-related quality of life (HRQOL) and high mortality risk, especially in the first year of treatment.
Avoiding arrythmias by personalizing the dialysate concentration: a case for precision medicine in patients on dialysis.
Kidney Int
January 2025
Sydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Cardiac arrythmias are common in patients undergoing maintenance hemodialysis. In this issue, Charytan et al. showed that in patients with hyperkalemia (serum potassium concentration 5.
View Article and Find Full Text PDFAutologous stem cell transplantation can potentially reverse dialysis dependence in patients with myeloma: Report of two cases and practical considerations.
Natl Med J India
October 2024
Department of Pathology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India.
Article Synopsis
- * Two dialysis-dependent patients underwent ASCT after partial recovery from treatment and received specific protocols, including a pre-emptive dialysis session and careful monitoring for complications.
- * Both patients showed positive outcomes post-transplant, with one being dialysis-free for 18 months and the other for 9 months before needing less frequent dialysis, indicating ASCT's potential benefits for this group despite inherent risks.
Distinct phenotyping of critical patients with demand-capacity imbalance initiating acute renal replacement therapy by consensus clustering.
J Formos Med Assoc
October 2024
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Article Synopsis
- Some patients who need dialysis have different chances of surviving and stopping treatment, so researchers looked for patterns among them.
- They studied over 900 patients to find three distinct groups based on their health and how they responded to dialysis.
- Results showed that one group did better, with higher survival rates and a better chance of stopping dialysis, while higher levels of a certain substance in blood (UCR) were linked to worse outcomes.
Exploring the mortality and cardiovascular outcomes with SGLT-2 inhibitors in patients with T2DM at dialysis commencement: a health global federated network analysis.
Cardiovasc Diabetol
September 2024
Primary Aldosteronism Center of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Article Synopsis
- Sodium-glucose cotransporter 2 inhibitors (SGLT-2is) may improve cardiovascular outcomes and overall survival for patients with type 2 diabetes mellitus who are starting dialysis.
- A study analyzed data from nearly 50,000 T2DM patients, finding that only 1.57% used SGLT-2is shortly after beginning dialysis, but those who did had significantly lower risks of major heart events and death.
- Safety outcomes were generally comparable between SGLT-2i users and non-users, with no notable increase in serious side effects or hospital readmissions after 90 days.
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