We made examinations (physical, clinical and laboratory) of 301 senior children and adolescents with varicocele admitted to Research Institute of Urology for the last 5 years. Spermatogenesis was assessed by WHO criteria for healthy men. 78% of the patients were operated by Ivanissevich, 22% received sclerotherapy. Sperm motility and morphological parameters were found subnormal. Taking into consideration relative subfertility of the patients, surgical results were positive. We continue follow-up of the patients and plan further studies of spermatogenesis.
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J Pediatr Urol
December 2024
Pediatric Urology Unit, Bambino Gesù Children Hospital and Research Center IRCCS, Rome, Italy.
Introduction: Vital dyes lymphography during laparoscopic varicocelectomy (LV) has been suggested to allow for lymphatic mapping thereby allowing for lymphatic sparing (LS) and subsequent reduction of hydrocele formation. Intratesticular injection of the dye seems to achieve the best lymphatic visualization, however, the potential toxicity of some agents, is a cause of concern for the risk of testicular pathological changes. We report our experience with LV, to test the hypothesis that Intraoperative lymphography with methylene blue (BL), is safe and reduces the rate of post-operative hydrocelectomy.
View Article and Find Full Text PDFKidney Res Clin Pract
November 2024
Department of Pediatrics, Korea University Ansan Hospital, Ansan, Republic of Korea.
Background: Nutcracker syndrome (NCS) has been reported to coexist with various glomerulonephritis (GN). This study investigated clinical features of NCS combined with GN in a pediatric case series and the possible relationship between these two conditions.
Methods: Clinical and pathologic findings of 15 children with NCS and biopsy-proven GN were analyzed.
Sci Rep
November 2024
Institute of Medical Sciences, General Hospital of Ningxia Medical University, Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan, 750004, China.
The study investigated the impact of varicocele on male infertility by analyzing sperm samples from 42 varicocele patients and 22 healthy individuals. Basic sperm parameters such as concentration and vitality were assessed, along with the DNA Fragmentation Index (DFI) using the SCSA method. Additionally, the mean number of sperm DNA breaks (MDB) and free DNA fragments amount in seminal plasma (fDFA) were analyzed using the TDT-Strand Displacement Probe Technique.
View Article and Find Full Text PDFAim: To evaluate the effect of microsurgical subinguinal varicocelectomy on sperm DNA fragmentation (SDF) in patients with elevated SDF levels (more than 15%) and clinical varicocele.
Materials And Methods: A single-center, retrospective, observational, uncontrolled study was carried out. The results of a survey of 33 patients with clinical varicocele, infertility or recurrent miscarriage and sperm DNA fragmentation of more than 15% were analyzed.
Andrology
November 2024
Desai Sethi Urology Institute, University of Miami, Miami, Florida, USA.
Background: Varicocele, a common vascular abnormality surrounding the testis, is known to be associated with impaired semen parameters and male infertility in adults. However, its impact on the adolescent and young adult (AYA) population is less well known.
Objectives: The study aimed to assess the improvement in sperm parameters following varicocelectomy in the AYA population, comparing them to matched adult counterparts, and investigating potential advantages of early intervention.
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