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Introduction: Evidence to support intra-operative lidocaine infusion regimens in patients with obesity is lacking, risking underdosing or toxicity. We aimed to measure the plasma concentrations of lidocaine and its active metabolites to develop a pharmacokinetic model and optimised dosing regimen in patients with obesity.

Methods: A standardised weight-based intravenous lidocaine regimen was administered to patients with a BMI ≥ 30 kg.

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Aims/background: Infertility diagnosis and related treatment can cause profound psychological discomfort and a variety of psychopathological symptoms. This study aims at investigating Referential Process linguistic measures applied to autobiographical memories of women facing fertility issues, hypothesising to find different elaboration and symbolisation capabilities according to the specific memories expressed.

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The combination of physiology and machine learning for prediction of CPAP pressure and residual AHI in OSA.

J Clin Sleep Med

January 2025

Division of Pulmonary, Critical Care, and Sleep Medicine, UC San Diego, San Diego, CA.

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Systolic Blood Pressure and Pulse Pressure in Heart Failure: Pooled Participant-Level Analysis of 4 Trials.

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Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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