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Background: Cardiac surgery patients are at increased risk for venous thromboembolism (VTE). Prevention is the most critical strategy to reduce VTE-associated morbidity and death. However, there is a lack of data on the optimal approach to VTE prophylaxis in this population of high-risk patients.

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Objective: Pulmonary embolism (PE) is the third leading cause of cardiovascular death. The objective of this study was to examine the current management of pulmonary embolism at a single academic institution.

Methods: With institutional review board approval, we conducted a retrospective chart review of 805 encounters among 775 patients presenting with acute PE from January 1, 2016 to June 30, 2019.

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Article Synopsis
  • This study investigates the safety and effectiveness of aspirin compared to enoxaparin for preventing blood clots in high-risk patients undergoing total joint surgeries, specifically total knee and hip arthroplasties.
  • Analyzing data from surgeries performed between 2015 and 2021, the researchers compared patients with a history of venous thromboembolism (VTE) who were given either aspirin or enoxaparin after their surgeries.
  • The findings suggest that patients on aspirin had similar rates of serious complications like pulmonary embolism and deep vein thrombosis as those on enoxaparin but experienced fewer bleeding-related issues and complications overall.
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Article Synopsis
  • The study investigates the effectiveness of enoxaparin, a medication for preventing blood clots, in critically ill children, focusing on differences in response based on age, particularly between older children and infants.
  • It consists of two simultaneous clinical trials: one for older children aged 1-17 years, and another for infants under 1 year, with specific dosing protocols for each group.
  • The trials are set in multiple pediatric intensive care units across the U.S., using methods like randomization, ultrasonography, and blood analysis to assess outcomes and monitor safety.
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Introduction: Compartment syndrome is a surgical emergency caused by elevated pressure within a closed fascial compartment, leading to compromised tissue perfusion and the potential for irreversible damage if not treated promptly. This report presents a rare case of upper limb compartment syndrome in a COVID-19 patient on anticoagulation therapy following multiple failed venipuncture attempts. This work has been reported in line with the SCARE criteria.

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