Clinical manifestations of laryngopharyngeal reflux.

Ear Nose Throat J

Center for Voice Disorders, Wake Forest University School of Medicine, Winston-Salem, N.C., USA.

Published: September 2002

Laryngopharyngeal reflux (LPR) is ubiquitous and associated with many head and neck symptoms and diagnoses. In some cases, the symptom is the diagnosis--for example, LPR can cause sore throat, chronic cough, globus pharyngeus, and laryngospasm. Alternately, LPR can be associated with specific histopathologic lesions--for example, vocal process granulomas. LPR can be the sole cause or an etiologic cofactor in the development of many disorders of the aerodigestive tract.

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