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Testicular plasmacytoma: report of a case and review of the literature. | LitMetric

Testicular plasmacytoma: report of a case and review of the literature.

Am J Hematol

Hematology and Bone Marrow Transplantation Unit, Azienda Ospedaliera S. Camillo/Forlanini, Rome, Italy.

Published: October 2002

AI Article Synopsis

Article Abstract

Plasmacytomas of the testis are rare neoplasias; they may occur as isolated tumors or in concomitance with generalized multiple myeloma. We report the case of a 77-year-old man with previous clinical evidence of multiple myeloma involving skin, ribs, and lungs, and initially treated with surgery, radiotherapy, and chemotherapy attaining partial response. Fourteen months after the onset, the patient presented with left testicular enlargement due to plasmacytoma. Immunohistochemical stains showed monoclonal cytoplasmic IgA-lambda in tumour cells; serum M component showed the same immunoglobulin. Following radiotherapy the tumour mass disappeared. Nonetheless, 2 months later while on chemotherapy, disease recurred with progressive increase of skeletal lesions. The patient is currently alive with disease progression 22 months after onset. On the basis of a review of the literature, the clinical significance of testicular myeloma localization is discussed.

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Source
http://dx.doi.org/10.1002/ajh.10174DOI Listing

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