Two antifungal proteins, named Eucommia antifungal peptides 1 and 2 (EAFP1 and EAFP2), have been purified from the bark of the tree E. ulmoides Oliver and show a relatively broad spectrum of antifungal activity against several agriculturally important plant pathogens. One of these small proteins (EAFP2) has been crystallized. The crystal belongs to space group P2(1), with unit-cell parameters a = 19.01, b = 23.16, c = 30.69 A, beta = 98.54 degrees. 1.0 A resolution data were collected from an EAFP2 crystal and have been used to obtain phase information directly by an ab initio method.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1107/s0907444902012131 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The efficient separation of bioactive components from Eucommia ulmoides Oliver using membrane filtration technology and its mechanisms in preventing alcoholic liver disease.
Carbohydr Polym
March 2025
College of Mechanical and Electronic Engineering, Northwest A&F University, Yangling 712100, China; College of Forestry, Northwest A&F University, Yangling 712100, China; Western Scientific Observation and Experiment Station for Development and Utilization of Rural Renewable Energy, M.O.A, Northwest Agriculture & Forestry University, Yangling 712100, China. Electronic address:
The efficient extraction and purification of active components from Eucommia ulmoides Oliver (EUO) are crucial for their utilization. The structure and properties of the prepared EUO leaf polysaccharides (ELPs) and extractum (ELE) were comprehensively characterized in this study, and the intervention mechanism of the EUO polysaccharides and extractum in alcoholic liver disease (ALD) were investigated. The yield of EUO extractum was 24.
View Article and Find Full Text PDFPrediction of the potentially suitable areas of Oliver in China under climate change based on optimized Biomod2 and MaxEnt models.
Front Plant Sci
November 2024
National Engineering Technology Research Center for Miao Medicine, Guizhou Engineering Technology Research Center for Processing and Preparation of Traditional Chinese Medicine and Ethnic Medicine, College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Oliver is a medicinal plant of significant economic importance. Its cortex has been employed for centuries to alleviate various conditions such as lumbar pain, knee pain, and osteoporosis. Additionally, possesses substantial industrial value.
View Article and Find Full Text PDFEucommia ulmoides Oliver polysaccharide alleviates glucocorticoid-induced osteoporosis by stimulating bone formation via ERK/BMP-2/SMAD signaling.
Sci Rep
November 2024
Department of Orthodontics, Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Osteoporosis (OP) is a metabolic disease characterized by low bone mineral mass owing to osteoblast dysfunction. Eucommia ulmoides Oliver (EuO) is a Chinese herbal medicine traditionally used to treat OP. Here, a polysaccharide purified from the EuO cortex (EuOCP3) was administered to OP mice constructed with dexamethasone (Dex) to investigate its anti-OP activity.
View Article and Find Full Text PDFPhytochemical component profiling and anti-renal fibrosis effects of crude and salt-stir fried Eucommiae Cortex extracts on renal fibrosis rats caused by high-purine diet.
Food Chem
February 2025
School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 310053, PR China. Electronic address:
A prolonged diet laden with purine-rich foods represents a significant contributor to renal fibrosis (RF). Eucommia ulmoides Oliver, a plant homologous to food and medicinal materials, has long been employed to recover kidney function. This investigation presents a strategy integrating chemistry, biochemistry, and metabolomics to evaluate bioactive components and efficiency mechanism of crude and salt-stir fried Eucommiae Cortex (EC) extracts against RF.
View Article and Find Full Text PDFKaempferol promotes osteogenic differentiation in bone marrow mesenchymal stem cells by inhibiting CAV-1.
J Orthop Surg Res
October 2024
Department of Traditional Chinese Medicine, Xi'an International Medical Center Hospital, No. 777, Xitai Road, High-tech Zone, Xi'an, 710117, Shaanxi, P.R. China.
Objective: Our study focused on the effects and molecular mechanisms of kaempferol, a major active component of Eucommia ulmoides Oliver (EUO), on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs).
Methods: Target molecules for EUO, osteoarthritis, and osteogenic differentiation were identified through network pharmacology analysis. BMSCs were isolated and treated with various concentrations of kaempferol.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!