A benchtop high-resolution time-of-flight mass spectrometer (TOF MS) was evaluated for the determination of key organic microcontaminants. The major advantage of the TOF MS proved to be the high mass resolution of about 0.002 Da (10 ppm). Consequently, the detectability of polar pesticides, polynuclear aromatic hydrocarbons and polychlorinated biphenyls is excellent, and detection limits are in the order of 1-4 pg injected mass. Best mass spectral resolution was obtained for medium-scale peaks. It is a disadvantage that the calibration range is rather limited, viz. to about two orders of magnitude. The high mass spectral resolution was especially useful to improve the selectivity and sensitivity when analyzing target compounds in complex samples and to prevent false-positive identifications.
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http://dx.doi.org/10.1016/s0021-9673(02)00233-9 | DOI Listing |
Talanta
January 2025
College of Pharmacy, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China; Department of Chemistry, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China. Electronic address:
B vitamins are essential for energy metabolism, nervous health, blood production, and the immune system. Their quantification in nutritional supplements and food is mandatory to manage a correct daily intake and dosage. In this study, a fast and sustainable method for the analysis of 8 B vitamins (VB, VB, VB, nicotinamide, VB, VB, VB, VB) in real samples using a 2D-carbon microfiber fractionation system combined with a triple quadrupole mass spectrometer (2DμCFs-QqQ-MS/MS) is presented.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Experimental Center of Advanced Materials, School of Materials Science & Engineering, Beijing Institute of Technology, Beijing, 100081, China.
The lunar soil samples returned by China's Chang'e-5 (CE-5) contain valuable information on geological evolutions on the Moon. Herein, by employing high-resolution time-of-flight secondary ion mass spectrometry (TOF-SIMS), five rock chip samples from the CE-5 lunar soil are characterized in-depth, which reveal micro-morphological and compositional features. From the elemental/molecular ion distribution images, minerals such as pyroxene, ilmenite, feldspar, K-rich glass, silica, and silicate minerals are identified, along with their occurrence states and distribution results.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.
This research was designed to investigate the metabolite profiling, phenolics content, and the trypanocidal, nematicidal, antibacterial, antifungal, and free radical scavenging properties of Motyka. The air-dried material was extracted successively with dichloromethane and methanol (UlMeOH). Two phases were obtained from the extract with dichloromethane, one soluble in methanol (UlDCM-s) and the other insoluble (UlDCM-i).
View Article and Find Full Text PDFJ Pharm Biomed Anal
January 2025
ADSI, Austrian Drug Screening Institute GmbH, Innrain 66a, Innsbruck 6020, Austria.
The aim of this work was to develop and validate a rapid dispersive-solid-phase extraction method for the quantification of pyrrolizidine alkaloids (PA) from plant extracts. The method was focused on the significant removal of the intricate matrix to ensure good sensitivity for the subsequent instrumental analysis of PA. This was achieved by employing nano-zirconium silicate (NZS) as a dispersive-SPE sorbent.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Science and Technology Branch, Pacific Environmental Science Centre, Environment and Climate Change Canada, Pacific and Yukon Laboratory for Environmental Testing, North Vancouver, BC, Canada.
Spilled plant-based oils behave very differently in comparison to petroleum oils and require different clean-up measures. They do not evaporate, disperse, dissolve, or emulsify to a significant degree but can polymerize and form an impermeable cap on sediment, smothering benthic media and resulting in an immediate impact on the wildlife community. The current study explored the application of rapid up-to-date direct analysis in real time (DART) with high-resolution mass spectrometry for plant-based oil typing.
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