Four stereoisomers of p-menthane-3,8-diol, which make up the natural product obtained from Eucalyptus citriodora, were synthesized through stereoselective procedures. Repellency assays showed that all the four were equally active against Anopheles gambiae s.s. Racemic blends and the diastereoisomeric mixture of all the four isomers were also equally repellent. 1-alpha-terpeneol, with a single hydroxyl function at C-8 and unsaturation at C-8, and menthol, with a single hydroxyl function at C-3, were not repellent. The practical implication of these results is discussed.

Download full-text PDF

Source
http://dx.doi.org/10.1603/0022-2585-39.5.736DOI Listing

Publication Analysis

Top Keywords

anopheles gambiae
8
single hydroxyl
8
hydroxyl function
8
repellent activities
4
activities stereoisomers
4
stereoisomers p-menthane-38-diols
4
p-menthane-38-diols anopheles
4
gambiae diptera
4
diptera culicidae
4
culicidae stereoisomers
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!