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Spatial QRS-T angle can indicate presence of myocardial fibrosis in pediatric and young adult patients with hypertrophic cardiomyopathy.

J Electrocardiol

December 2024

Crown Princess Victoria Children's Hospital, Dept of Biomedical and Clinical Sciences, Dept of Pediatrics, Linköping University, Sweden; Pediatric Heart Centre, Skåne University Hospital and Dept of Clinical Sciences, Lund University, Sweden. Electronic address:

Background: Myocardial fibrosis, expressed as late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR), is an important risk factor for malignant cardiac events in hypertrophic cardiomyopathy (HCM). However, CMR is not easily available, expensive, also needing intravenous access and contrast.

Objective: To determine if derived vectorcardiographic spatial QRS-T angles, an aspect of advanced ECG (A-ECG), can indicate LGE to appropriately prioritize young HCM-patients for CMR.

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Re-evaluating the electro-vectorcardiographic criteria for left bundle branch block.

Ann Noninvasive Electrocardiol

July 2019

Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

The criteria for left bundle branch block have gained growing interest in the last few years. In this overview, we discuss diagnostic and prognostic aspects of different criteria. It was already shown that stricter criteria, including longer QRS duration and slurring/notching of the QRS, better identify responders to cardiac resynchronization therapy.

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Left posterior fascicular block, state-of-the-art review: A 2018 update.

Indian Pacing Electrophysiol J

October 2018

Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Finland.

We conducted a review of the literature regarding epidemiology, clinical, electrocardiographic and vectorcardiographic aspects, classification, and differential diagnosis of left posterior fascicular block. Isolated left posterior fascicular block (LPFB) is an extremely rare finding both in the general population and in specific patient groups. In isolated LPFB 20% of the vectorcardiographic (VCG) QRS loop is located in the right inferior quadrant and when associated with right bundle branch block (RBBB) ≥40%.

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Electro-vectorcardiographic and electrophysiological aspects of Ebstein's anomaly.

Ann Noninvasive Electrocardiol

May 2019

Heart Center, Faculty of Medicine and Life Sciences, Tampere University Hospital, University of Tampere, Tampere, Finland.

Ebstein's anomaly is a congenital heart disease where the most important anatomic feature is the inferior displacement of the tricuspid valve leaflets. Vectorcardiographic features are mainly forgotten and electrocardiographic features may be unrecognized by cardiologists handling adult patients.

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Background: The J-wave electrocardiographic patterns include early repolarization (ER) and Brugada syndrome; especially when ER is located in the anteroseptal leads (V1-V3), it can mimic the Brugada syndrome (BrS) ECG pattern and therefore mislead the diagnosis. We aimed to define the vectorcardiographic characteristics of BrS and ER using aspects of QRS complex loop, J-point and ST-segment.

Methods/results: Vectorcardiographic loops in the transverse plane (TP) of 14 BrS patients and 26 individuals with ER were analyzed and defined, and then a third group of 17 patients with non-characteristic ECG patterns were analyzed and compared with them.

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