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Biphasic effect of limonene on contraction of isolated rat aorta.
Chem Biol Interact
January 2025
Department of Biological Chemistry, Regional University of Cariri, 63105-000, Crato, CE, Brazil.
Article Synopsis
- Limonene, a compound in essential oils, demonstrates various health benefits like antifungal and antioxidant properties, but its effects can vary based on concentration, showing a biphasic response.
- The study investigates limonene's impact on rat aorta contractions, revealing it can enhance or inhibit contractions depending on the dose, particularly with phenylephrine.
- Understanding these dose-dependent effects is crucial for determining safe and effective therapeutic uses of limonene in clinical settings.
Muscle Tone Assessment by Machine Learning Using Surface Electromyography.
Sensors (Basel)
September 2024
Assistive Technology Laboratory, Faculty of Electrical Engineering, Federal University of Uberlandia, Uberlandia 38400-902, Brazil.
Muscle tone is defined as the resistance to passive stretch, but this definition is often criticized for its ambiguity since some suggest it is related to a state of preparation for movement. Muscle tone is primarily regulated by the central nervous system, and individuals with neurological disorders may lose the ability to control normal tone and can exhibit abnormalities. Currently, these abnormalities are mostly evaluated using subjective scales, highlighting a lack of objective assessment methods in the literature.
View Article and Find Full Text PDFEvaluating heart rate variability by a novel stethoscopic approach to minimise stress in cats.
J Feline Med Surg
October 2024
National Taiwan University Veterinary Hospital, National Taiwan University, Taipei, Taiwan.
Article Synopsis
- The study aimed to find a stress-free method for evaluating heart rate variability (HRV) in cats using a stethoscope instead of traditional ECG recordings, which can cause stress during the process.
- Researchers recorded heart sounds from 29 cats in relaxed and stimulated states, calculating a new measure called the vasovagal tonus index (VVTI) to assess autonomic function.
- Results showed that the stethoscopic VVTI significantly decreased after stimulation, indicating reduced vasovagal tone, with findings being comparable between at-home and hospital settings, thus validating this cat-friendly approach.
Coronary microvascular dysfunction and autoregulatory capacity interfere with resting Dicrotic notch morphology.
Microvasc Res
January 2025
Department of Cardiology, Acibadem International Hospital, Istanbul, Turkey. Electronic address:
Coronary microvascular vasodilator capacity is substantially associated with coronary pressure waveform and dicrotic notch morphology, with or without concomitant epicardial disease. A prominent dicrotic notch is associated with preserved microvascular vasodilatory capacity and adequate resting microvascular tonus without relative hyperaemic state, cumulatively indicating a better microcirculatory health.
View Article and Find Full Text PDFNew results in stereopsis and Listing's law.
Sci Rep
September 2024
Professor Emeritus, Department of Mathematics and Statistics, University of Houston-Downtown, One Main Street, Houston, TX, 77002, USA.
Human eyes' optical components are misaligned. This study presents comprehensive geometric constructions in the binocular system, with the eye model incorporating the fovea that is displaced from the posterior pole and the lens that is tilted away from the eye's optical axis. It extends their previously considered horizontal misalignment with the vertical components.
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