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Cerebral vein thrombosis: management tactics with a focus on pregnancy, the use of hormone therapy and assisted reproductive technologies.
J Matern Fetal Neonatal Med
December 2025
Department of Obstetrics, Gynecology and Perinatal Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Cerebral vein thrombosis is a rare, life-threatening condition that has now become more commonly diagnosed due to advancements in imaging techniques. Our purpose is to improve understanding of pathogenesis, diagnosis and pregnancy and IVF management in patients with a history of cerebral thrombosis. We present an overview of the modern tactics of anticoagulant therapy for cerebral thrombosis with a focus on pregnancy, the use of hormone therapy, and assisted reproductive technologies.
View Article and Find Full Text PDFArticle Synopsis
- - Postpartum venous thromboembolism (VTE) is a serious complication that can occur after childbirth, driven by factors like increased blood clotting, reduced mobility, and injury to blood vessels, leading to high risks for new mothers.
- - A case study details a 37-year-old woman with a history of recurrent clots and pregnancy issues that ultimately resulted in severe chronic venous obstruction despite various treatments, necessitating advanced procedures like stent implantation.
- - The patient's medical journey involved multiple challenges, including spontaneous abortions, a pulmonary embolism linked to contraceptive use, and serious complications during and after her last pregnancy, highlighting the importance of careful monitoring and effective prevention strategies for postpartum VTE.
The subject of this guideline from the Institute of Family Medicine at the University of Zurich (IHAMZ) is the management of venous thrombosis. The review summarizes the current evidence and recommendations from international guidelines (1-6). The IHAMZ-guidelines focus on primary care, they also provide guidance on the coordination of general and specialist medical care as well as on the transition between outpatient and hospital care taking into account the special features of the Swiss healthcare system.
View Article and Find Full Text PDFA 27-Year-Old Female With JAK2 Mutation: A Case of Budd-Chiari Syndrome Secondary to Prolonged Oral Contraceptive Pill Use.
Cureus
July 2024
Family Medicine, Henry Ford Health System, Detroit, USA.
Article Synopsis
- * A case study of a 27-year-old female with ET and a history of ulcerative colitis highlights the dangers of using estrogen-containing oral contraceptive pills, which contributed to her serious condition involving obstructive jaundice and thrombosis in major veins.
- * The successful transjugular intrahepatic portosystemic shunt procedure she underwent illustrates the critical need for cautious medication management and vigilant monitoring in patients with hypercoagul
Portal vein thrombosis: diagnosis, management, and endpoints for future clinical studies.
Lancet Gastroenterol Hepatol
September 2024
Centre de recherche sur l'inflammation, Université Paris-Cité, Paris, France; Service d'Hépatologie, AP-HP Hôpital Beaujon, Clichy, France. Electronic address:
Portal vein thrombosis (PVT) refers to the development of a non-malignant obstruction of the portal vein, its branches, its radicles, or a combination. This Review first provides a comprehensive overview of all aspects of PVT, namely the specifics of the portal venous system, the risk factors for PVT, the pathophysiology of portal hypertension in PVT, the interest in non-invasive tests, as well as therapeutic approaches including the effect of treating risk factors for PVT or cause of cirrhosis, anticoagulation, portal vein recanalisation by interventional radiology, and prevention and management of variceal bleeding in patients with PVT. Specific issues are also addressed including portal cholangiopathy, mesenteric ischaemia and intestinal necrosis, quality of life, fertility, contraception and pregnancy, and PVT in children.
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