Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/1521-3773(20020916)41:18<3485::AID-ANIE3485>3.0.CO;2-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Microcrystal Growth Pathways Investigated with Machine Learning Segmentation and Classification in Scanning Electron Microscopy.
ACS Nano
December 2024
Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.
Advances in electron microscopy have revolutionized material characterization on the nano- and microscales, providing important insights into local ordering, structure, and size and quality distributions. While shape and size can be rigorously quantified through microscopy, it is often limited to local structure analysis and fails to describe bulk sample quality. Herein, a flexible machine learning (ML) tool is described that can segment and classify faceted crystals in scanning electron microscopy (SEM) micrographs to determine sample quality through the crystal size and product distribution.
View Article and Find Full Text PDFFluorescence Quenching Dynamics of 2-Amino-7-methyl-1,8-naphthyridine in Abasic-Site-Containing DNA Duplexes for Nucleobase Recognition.
J Phys Chem Lett
November 2023
College of Chemistry, Beijing Normal University, Beijing 100875, People's Republic of China.
Dramatic fluorescence quenching of small heterocyclic ligands trapped in the abasic site (AP) of DNA has been implemented as an unprecedented strategy recognizing single-base mutations in sequence analysis of cancer genes. However, the key mechanisms governing selective nucleobase recognition remain to be disentangled. Herein, we perform fluorescence quenching dynamics studies for 2-amino-7-methyl-1,8-naphthyridine (AMND) in well-designed AP-containing DNA single/double strands.
View Article and Find Full Text PDFMutual promotion of mitochondrial fission and oxidative stress contributes to mitochondrial-DNA-mediated inflammation and epithelial-mesenchymal transition in paraquat-induced pulmonary fibrosis.
World J Emerg Med
January 2023
Department of Emergency Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Background: Pulmonary fibrosis (PF) is one of the main causes of death in patients with paraquat (PQ) poisoning. This study aimed to evaluate the relationship between mitochondrial fission and oxidative stress in PQ-induced epithelial-mesenchymal transition (EMT) and PF.
Methods: C57BL/6 mice and MLE-12 cells were exposed to PQ to construct a PF model and .
Arrays of Colloidal Single Crystals Engineered with DNA in Lithographically Defined Microwells.
Nano Lett
January 2023
Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.
Lithographically defined microwell templates are used to study DNA-guided colloidal crystal assembly parameters, including superlattice position, habit orientation, and size, in an effort to increase our understanding of the crystallization process. In addition to enabling the synthesis of arrays of individual superlattices in arbitrary predefined patterns, the technique allows one to study the growth pathways of the crystals via scanning electron microscopy. Importantly, a Volmer-Weber (VM) (island formation)-like growth mode is identified, which has been reproduced via simulations.
View Article and Find Full Text PDFReactivity of a nitrosyl ruthenium complex and its potential impact on the fate of DNA - An in vitro investigation.
J Inorg Biochem
January 2023
Bioinorganic Group, Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, CE 60451-970, Brazil. Electronic address:
The role of metal complexes on facing DNA has been a topic of major interest. However, metallonitrosyl compounds have been poorly investigated regarding their reactivities and interaction with DNA. A nitrosyl compound, cis-[Ru(bpy)(SO)(NO)](PF)(A), showed a variety of promising biological activities catching our attention.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!