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[Analysis of the current status and influencing factors of enteral nutrition intolerance in intensive care unit patients].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue

December 2024

Department of Nursing, Guizhou Provincial People's Hospital, Guiyang 550004, Guizhou, China. Corresponding author: Yao Huan, Email:

Objective: To investigate the current status and influencing factors of feeding intolerance (FI) during enteral nutrition (EN) in intensive care unit (ICU) patients.

Methods: A retrospective case-control study was conducted, including patients from two ICU wards of a tertiary hospital in Guizhou Province from July 2019 to December 2022. Clinical data were collected using a self-designed data collection form, including general information [age, gender, acute physiology and chronic health evaluation II (APACHE II)], clinical treatment (mechanical ventilation, mild hypothermia therapy), medication use (vasoactive drugs, glucocorticoids, analgesics, sedatives), EN implementation (types of EN fluids, EN methods, tube feeding rate), EN tolerance, and blood glucose status.

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Article Synopsis
  • Postoperative nutritional support is crucial for improving recovery and outcomes in patients with gastrointestinal cancer, with enteral and parenteral nutrition being key strategies.
  • A meta-analysis of 11 randomized controlled trials found that combining enteral nutrition (EN) with parenteral nutrition (PN) significantly enhances recovery, nutritional function, and immune response compared to using either method alone.
  • The study also revealed that the EN-only group had a higher risk of postoperative complications, such as nausea, vomiting, and diarrhea, indicating that combined nutrition may have better overall safety and efficacy.
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Clinical effects of pediatric commercial food-based formulas: A systematic review.

J Pediatr Gastroenterol Nutr

December 2024

Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.

Blenderized tube feeding (BTF) uses a feeding tube to deliver blended whole foods directly to the gastrointestinal (GI) system and has had renewed interest over the last two decades. This was initially delivered in the form of homemade BTF (HBTF) and led to the development of commercial food-based formula (CFBF). The safety and clinical outcome data for CFBF are limited.

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Aim: Patients with gastric malignant tumors usually undergo surgical treatment when indicated. Surgical intervention causes significant trauma and can lead to considerable stress responses in patients. These patients experience increased malnutrition along with reduced immune function, which ultimately leads to the occurrence of postoperative complications.

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Background: Several studies revealed the beneficial effects of probiotics against the incidence of antibiotic-associated diarrhea of hospitalized patients but it is rarely to assess the nutrition status. This study investigated the effects of probiotics in elderly hospitalized tube-fed patients with antibiotics use and is the first study that concerns the nutritional status among these patients.

Methods: Elderly hospitalized tube-fed patients who were using antibiotics were recruited.

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