A study was made of the effect of the thyroid hormone thyrocalcitonin (TCT) on the electrolyte composition of the plasma and erythrocytes. In healthy persons and in the patients with various diseases of the cardiovascular system administration of 1 Unit of TCT per 1 kg of weight led to a significant reduction of the total plasma calcium and its diffusible fraction and also of plasma sodium. A course treatment with the hormone led to the enhancement of the hypocalciemic effect. In dogs administration of 10 Units of TCT per 1 kg of weight produced a more pronounced hypocalciemic effect. The rest of blood electrolytes displayed no significant changes.
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