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Recent advances in osteoarthritis research: A review of treatment strategies, mechanistic insights, and acupuncture.
Medicine (Baltimore)
January 2025
The Third Affiliated Hospital of Xinxiang Medical University, Henan, China.
Osteoarthritis (OA) is a chronic joint condition affecting millions worldwide, characterized by the gradual degeneration of joint cartilage, leading to pain, stiffness, and functional impairment. Although the pathogenesis of OA is not fully understood, the roles of inflammation, metabolic dysregulation, and biomechanical stress are increasingly recognized. Current treatments, including pharmacotherapy, physical therapy, and surgical interventions, aim to alleviate symptoms and improve quality of life, yet they face limitations and challenges.
View Article and Find Full Text PDFA 4-Week Mobile App-Based Telerehabilitation Program vs Conventional In-Person Rehabilitation in Older Adults With Sarcopenia: Randomized Controlled Trial.
J Med Internet Res
January 2025
Department of Rehabilitation Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Sarcopenia is closely associated with a poor quality of life and mortality, and its prevention and treatment represent a critical area of research. Resistance training is an effective treatment for older adults with sarcopenia. However, they often face challenges when receiving traditional rehabilitation treatments at hospitals.
View Article and Find Full Text PDFCan strengthening digital infrastructure enhance productivity in the cultural industry? evidence from Tibet.
PLoS One
January 2025
School of Economics and Management, Tibet University, Lhasa, Tibet Autonomous Region, China.
This study, grounded in the Total Factor Productivity (TFP) theoretical framework, examines the impact of digital infrastructure on the productivity of Tibet's cultural industry from 2011 to 2021. It aims to uncover how the innovative allocation of production factors can enhance new-quality productivity. The core aspect of new-quality productivity is the improvement of TFP, with digital infrastructure promoting the cultural industry's development by optimizing industrial agglomeration, improving logistics efficiency, and reducing the urban-rural consumption gap.
View Article and Find Full Text PDFHydraulic performance of a pre-aerated stilling basin: Experimental study.
PLoS One
January 2025
School of Hydraulic Engineering, Zhejiang University of Water Resources and Electric Power, Hangzhou, Zhejiang, China.
Spillway chutes are critical in dam flood control, particularly in high dams where high water heads and large discharge in narrow canyons amplify the demand for safe discharging. For large unit discharges in spillways, aeration protection is essential to prevent cavitation erosion, but challenges arise from air duct choking in the traditional spillway and nonaerated regions in the stepped spillway. This paper introduces a novel spillway called the pre-aerated stilling basin spillway (PSBS).
View Article and Find Full Text PDFInsights into the representativeness of biodiversity assessment in large reservoir through eDNA metabarcoding.
PLoS One
January 2025
Bio Bureau Biotechnology, Rio de Janeiro, Rio de Janeiro, Brazil.
Monitoring biodiversity on a large scale, such as in hydropower reservoirs, poses scientific challenges. Conventional methods such as passive fishing gear are prone to various biases, while the utilization of environmental DNA (eDNA) metabarcoding has been restricted. Most eDNA studies have primarily focused on replicating results from traditional methods, which themselves have limitations regarding representativeness and bias.
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