AI Article Synopsis

  • Researchers synthesized a vinyl fluoride analogue based on an intermediate involved in reactions catalyzed by type II dehydroquinase enzymes.
  • The synthesis process took seven steps, starting from (-)-quinic acid.
  • This analogue has been identified as a strong inhibitor of the enzyme, indicating potential for future research or applications.

Article Abstract

A vinyl fluoride analogue of the intermediate in the reaction catalysed by type II dehydroquinase enzymes has been synthesized over seven steps from (-)-quinic acid and shown to be a potent enzyme inhibitor.

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Source
http://dx.doi.org/10.1039/b205105mDOI Listing

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