[TREATMENT OF PEPTIC ULCER].

Peptic ulcer disease has been the reason for extensive studies throughout the 20th Century. During the first 75 years, investigation and study of the production of acid and in which cases it leads to the formation of ulcers were carried out. The last 25 years have been of major importance due to the finding of powerful suppressants of acid formation. At first, the Histamine H2-antagonist, then the blockers of the proton bomb; and also the Helicobacter pylori finding, as an important factor in peptic ulcer disease. During these last years, studies report about how the Helicobacter pylori works in the stomach of patients who are liable to produce ulcers. Now, we also know more about the action of the antiulcerative drugs, and how to use them in the best way. Lately, the recurrence of peptic ulcer and bacterial resistance of the Helicobacter pylori are concepts that are being studied most profoundly.