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Influence of kinesiophobia on activity, function, and anxiety levels in patients with rheumatoid arthritis.
Front Med (Lausanne)
January 2025
Health Management Center, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder that causes joint inflammation and affects quality of life. Appropriate physical activity can enhance joint function and lower cardiovascular disease risk. However, individuals with RA often have reduced physical activity levels, likely due to kinesiophobia, or fear of movement.
View Article and Find Full Text PDFIdiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations: A Case Report.
Cureus
December 2024
Internal Medicine, Unidade Local De Saúde De São João, Porto, PRT.
Hypereosinophilic syndrome (HES) is marked by eosinophilic infiltration and the release of inflammatory mediators that cause damage to multiple organs. Despite careful evaluation of hypereosinophilia, the etiology of most cases remains undefined. Eosinophils may cause damage in almost all organs, and most patients present with dermatological manifestations.
View Article and Find Full Text PDFImpact of glucocorticoids on the therapeutic efficacy of denosumab against osteoporosis in patients with rheumatoid arthritis.
Ther Adv Musculoskelet Dis
January 2025
Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea.
Background: Rheumatoid arthritis (RA) and prolonged high-dose glucocorticoid (GC) treatment are established risk factors for osteoporosis.
Objectives: In this study, we aimed to evaluate the therapeutic efficacy of denosumab according to the GC dose considered to increase the risk of glucocorticoid-induced osteoporosis (GIOP) in patients with RA.
Design: A retrospective analysis of collected data on RA patients with osteoporosis starting denosumab.
C2 Vertebra: An Enigma for Young Spine/Neurosurgeons.
J Neurol Surg B Skull Base
February 2025
Department of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Instrumentation of C2 vertebra is considered the most difficult for young neurosurgeons and trainees due to its complex anatomical structures, variety of surgical approaches and techniques, and proximity to important neurovascular structures. Key points from a surgical perspective for midline posterior approach is described in the era of neuroradiological advancements. Computed tomography angiographies (CTAs) of a total of 92 patients were evaluated with special attention to the key findings for insertion of screws for craniovertebral junction (CVJ) fixations.
View Article and Find Full Text PDFEffect of Rheumatoid Arthritis on Postoperative Outcomes in Patients with Lumbar Spinal Disorders: A Systematic Review and Meta-Analysis.
Global Spine J
January 2025
Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Study Design: A systematic review and meta-analysis.
Objective: This study aimed to determine whether rheumatoid arthritis (RA) is associated with clinical outcomes following spinal surgery for lumbar spinal disorders.
Methods: MEDLINE, Embase, the Cochrane Library, and the International Clinical Trials Registry Platform were comprehensively searched for observational studies comparing clinical outcomes after lumbar spine surgery in patients with and without RA (>18 years).
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