A morphometric investigation was made on mitochondria of basalioma cells and the cells of the basal layer of the epidermis lying over the tumor. The mitochondria of the basalioma cells occupy 4.7% and of the epidermal basal cells 5.3% of the cytoplasm. The number of mitochondrial sections yields a relation of 6.6:10 in favor of the epidermal cells. These results demonstrate an alteration in the size of the basalioma cell mitochondria. The possible causes of this mitochondria enlargement were discussed. An attenuation of the activities of the mitochondrial, membrane-bound enzymes in the basalioma cells is caused in all probability primarily by a reduction of the cristae material in comparison to the basal epidermal cells. The nucleus-cytoplasm relation amounts to 6.3:10 in the basalioma cells and 3.0:10 in the basal epidermal cells.
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