Serum cholinesterase activity (ChE) was studied in 84 patients with chronic liver diseases (cirrhosis, chronic hepatitis, chronic cholecystocholangiohepatitis, hepatolenticular degeneration). Most pronounced alterations were found in cirrhosis. Significant difference is not established between cardiac and "noncardiac" cirrhosis but is well established between decompensated and compensated cirrhosis. As a rule ChE is normal in chronic hepatitis and cholecystocholangio-hepatitis. The values in agressive and persisting hepatitis do not differ significantly. Essential correlation of ChE with serum albumins is established. The diagnostic ChE value is confronted with that of the routine laboratory indices. Critical values are established (1500 ME, 1100 ME resp) that may be helpful in the differentiation of cirrhosis from chronic hepatitis, compensated from decompensated cirrhosis resp.
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