[The weakest link: medroxyprogesterone acetate in pig feed].

Tijdschr Diergeneeskd

Hoofdafdeling Gezondheidszorg Landbouwhuisdieren, Afdeling Varkensgezondheidszorg, Faculteit der Diergeneeskunde, Utrecht.

Published: September 2002

Medroxyprogesterone acetate (MPA)-contaminated feed arrested the onset of farrowing, and induced post-lactational anoestrus in sows. Sixty percent of the sows developed cystic ovaries after weaning following exposure to pharmaceutical waste of MPA in glucose syrup. This waste ended up in acidified feed of by-products of a sow farm, and proved to be the cause of the disorders. Analysis by thin layer chromatography and Gas Chromatography/Mass Spectrometry of renal fat from 10 slaughter sows demonstrated residues of 2.5-8 ppb of MPA. Within the European Union use of MPA is illegal as growth promoter in production animals, and therefore MPA-exposed farms were placed under official control by the general inspection service. Clinical signs and diagnostic procedures of the initial case are presented and the role of the veterinary practitioner in detecting potential food safety hazards is discussed.

Download full-text PDF

Source

Publication Analysis

Top Keywords

medroxyprogesterone acetate
8
[the weakest
4
weakest link
4
link medroxyprogesterone
4
acetate pig
4
pig feed]
4
feed] medroxyprogesterone
4
acetate mpa-contaminated
4
mpa-contaminated feed
4
feed arrested
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!