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A Comprehensive Insight into Apoptosis: Molecular Mechanisms, Signaling Pathways, and Modulating Therapeutics.
Cancer Invest
January 2025
Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
Article Synopsis
- Apoptosis, or programmed cell death, is vital for tissue balance, and its disruption is linked to diseases like cancer and neurodegenerative disorders.
- The review explores the molecular mechanisms and signaling pathways of apoptosis, including how the tumor microenvironment affects treatment resistance in cancer.
- It also discusses new therapeutic strategies, including natural compounds and dietary supplements, that aim to modify apoptotic processes to improve disease management and cancer treatment outcomes.
Effects of Chinese herbal treatment and biofeedback electrical stimulation on pelvic floor muscle strength and quality of life in patients with postpartum stress urinary incontinence.
Afr J Reprod Health
November 2024
Meng Research Institute, Changzhou Hospital of Traditional Chinese Medicine, Chang Zhou 213003, Jiangsu, China.
This was an original article, and mainly evaluated the impacts of Buzhong Yiqi decoction and biofeedback electrical stimulation on pelvic floor muscle strength and the quality of life in patients with postpartum stress urinary incontinence (PSUI). PSUI patients (total = 256) were randomly selected into a control group and study group. The control group adopted pelvic floor muscle rehabilitation training only while the study group added Buzhong Yiqi decoction and biofeedback electrical stimulation.
View Article and Find Full Text PDFQuantification of Lawsone and p-Phenylenediamine in Natural Henna Products for Hair Colouring Available in Poland.
Contact Dermatitis
January 2025
Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn, Poland.
Background: Henna is a powdered plant material traditionally used for medicinal and cosmetic purposes in Asia and the Mediterranean region. In North America and Europe, however, it is only used to colour the hair and decorate the body. This colouring process is due to the action of the secondary metabolite lawsone, which enables henna to produce orange to red shades of colour.
View Article and Find Full Text PDFPreparation, characterization, and stability of selenium nanoparticles decorated with Mori Fructus polysaccharide and its protective effects in bisphenol A-induced Sertoli cells.
Int J Biol Macromol
January 2025
College of Engineering/National R&D Center for Chinee Herbal Medicine Processing, China Pharmaceutical University, Nanjing 211198, Jiangsu, China. Electronic address:
Bisphenol A (BPA) is an endocrine disruptor universally present in food packaging, which may cause oxidative stress and reproductive toxicity through migration to food and ingestion then. Both Mori Fructus and selenium have excellent antioxidant ability and good therapeutic effects on reproductive improvement. Hence, in this work, Mori Fructus polysaccharide (MFP) was selected as a stabilizer to synthesize MFP‑selenium nanoparticles (MFP-SeNPs) by chemical reduction method.
View Article and Find Full Text PDFThymine-capped mesoporous silica nanoparticles as ion-responsive release system: A paper-based colorimetric sensing platform for rapid and selective mercuric identification.
Biosens Bioelectron
December 2024
School of Pharmacy, Xi'an Medical University, Xi'an, 710021, China; Institute of Medicine, Xi'an Medical University, Xi'an, 710021, China. Electronic address:
In this study, a convenient method was proposed for the synthesis of thymine-capped mesoporous silica nanoparticles (MSN) using strong hydrogen bonding in non-protonic solvent. Furthermore, application of the functionalized MSN for the recognition of mercuric ion (Hg) based on a paper-based platform with smartphone-assisted colorimetric detection was developed. The synthesized materials were characterized by techniques including X-ray diffraction (XRD), fourier-transform infrared spectroscopy (FTIR), N adsorption-desorption, particle size analysis, transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA).
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