After a critical review of the literature and an enquiry based on 70 cases, the author confirms that osteogenic sarcomas and fibrosarcomas constitute the usual means of sarcomatous degeneration in bones affected by Paget's disease. Giant-cell tumours present a distinct group. The problems posed by the initial stages of the malignant transformation and the osteosarcomas with multiple centres are then discussed.
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Rare Tumors
September 2024
Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, India.
Diagn Cytopathol
December 2024
Cytology Unit, Dubai Hospital, Dubai, UAE.
J Surg Case Rep
August 2023
Department of Gynecology and Gynecological Oncology, AZ Sint-Jan Hospital Bruges, Bruges, Belgium.
Leiomyosarcomas of the uterine cervix are rare, mostly occurring in perimenopausal women. Diagnosis is based on pathology and immunohistochemistry. Surgery with a total abdominal hysterectomy and bilateral salpingo-oophorectomy remains the standard.
View Article and Find Full Text PDFWorld J Surg Oncol
June 2023
Department of Urology, Peking University Third Hospital, Haidian District, Beijing, 100191, People's Republic of China.
Background: Targeted therapy combined with immunotherapy is the current first-line treatment for metastatic renal cell carcinoma (mRCC), but patients with tumor thrombus (TT) may suffer from lower limb edema or even sudden cardiac death, so the purpose of this study is to investigate the efficacy and safety of surgical treatment in patients with mRCC and TT and explore worse factors to affect the prognosis in this series of patients.
Patients And Methods: A total of 85 mRCC patients with TT who received cytoreductive nephrectomy and thrombectomy at our medical center from 2014 to 2023 are included. All patients received postoperative systemic therapy.
J Craniofac Surg
September 2022
Medstar Georgetown University Hospital, Department of Otolaryngology-Head and Neck Surgery, Washington, DC.
Background: Fibrous dysplasia (FD) is an uncommon bone disease characterized by the replacement of normal bone architecture with abnormal fibro-osseous connective tissue. Here, we discuss 2 cases of craniofacial FD, with malignant sarcomatous degeneration - a rare and morbid complication of the disease.
Case History: Two cases of craniofacial FD with malignant degeneration are presented.
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