The number of distinct sites visited by a lattice random walker is a subject of continuing interest in both mathematics and physics. All previous investigations have used the assumption that the lattice is unbounded. An assessment of the amount of tissue interrogated by a photon in reflectance measurements for diagnostic purposes suggests analyzing properties of the average number of distinct sites visited by a random walker trapped by an absorbing plane at time t. We show that for sufficiently large t this number is the same as the average number of distinct sites visited for this time when the surface is not present. A more complete analysis is possible for a random walk on a line terminated by an absorbing point.
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http://dx.doi.org/10.1103/PhysRevE.66.012901 | DOI Listing |
Psychol Res
December 2024
Brain and Cognition, KU Leuven, Leuven, Belgium.
Researchers in numerical cognition have extensively studied the number sense-the innate human ability to extract numerical information from the environment quickly and effortlessly. Much of this research, however, uses abstract stimuli (e.g.
View Article and Find Full Text PDFPhytother Res
December 2024
Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt.
(1) Background and aim: Aloe arborescens Mill. (A. arborescens) is one of the most widely distributed species in the genus Aloe and has garnered widespread recognition for its anticancer properties.
View Article and Find Full Text PDFCancer Sci
December 2024
Department of Molecular Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan.
Patient-derived organoids represent a novel platform to recapitulate the cancer cells in the patient tissue. While cancer heterogeneity has been extensively studied by a number of omics approaches, little is known about the spatiotemporal kinase activity dynamics. Here we applied a live imaging approach to organoids derived from 10 pancreatic ductal adenocarcinoma (PDAC) patients to comprehensively understand their heterogeneous growth potential and drug responses.
View Article and Find Full Text PDFClin Genet
December 2024
Recanati Genetics Institute, Beilinson Hospital, Rabin Medical Center, Petach Tikva, Israel.
This retrospective cohort study aimed to define the optimal Regions of Homozygosity (ROH) size cut-offs for prediction of morbidity, based on 13 483 Chromosomal Microarray Analyses (CMA). Receiver operating characteristic (ROC) curves were generated, and area under the curve (AUC) was used to assess the predictive capability of total ROH percentage (TRPS), ROH number and ROH segment size in distinguishing between healthy (n=6,196) and affected (n=6,839) cohorts. The metrics were examined for telomeric and interstitial segments, distinct TRPS categories, and across different ancestral origins.
View Article and Find Full Text PDFJ Transl Med
December 2024
Department of Gastrointestinal Surgery, School of Medicine, RenJi Hospital, Shanghai Jiao Tong University, 160 Pujian Road, Pudong New Area, Shanghai, 200025, China.
Background: Recent studies have highlighted the distinct ratio of PD-1 + Treg/PD-1 + CD8 for prognosis prediction. However, it remains unclear about the association of this ratio and tertiary lymphoid structures (TLS) with prognosis and response to neoadjuvant or conversion therapy in advanced gastric cancer.
Methods: Firstly, fresh postoperative samples from 68 gastric cancer patients in Renji Hospital were collected.
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