Treatment of adult guinea pigs with prostaglandins produces changes in the levels of enzymes involved in carbohydrate metabolism of the thyroid gland. A decrease in glucose-6-phosphate dehydrogenase activity is observed with a concomitant increase in 6-phosphogluconic dehydrogenase; the glycolytic enzymes appear unaffected by the same treatment. The results indicate that prostaglandins do not have the biochemical effects obtained with thyrotropin and cAMP administration, showing that these compounds play an antagonistic role in comparison with the above mentioned stimulating agents.

Download full-text PDF

Source

Publication Analysis

Top Keywords

enzymes involved
8
carbohydrate metabolism
8
prostaglandins vivo
4
vivo enzymes
4
involved thyroid
4
thyroid carbohydrate
4
metabolism treatment
4
treatment adult
4
adult guinea
4
guinea pigs
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!