AI Article Synopsis
- Scientists studied older people in a hospital to find out why some get Clostridium difficile infections more than once, called recurrent C. difficile-associated diarrhea (RCDAD).
- They compared 43 patients who had RCDAD with 38 patients who only had one episode and found that more than half of the patients had recurrent infections.
- Risk factors for getting RCDAD included having trouble controlling bowel movements, being sick with a fever for a longer time, and taking certain medications.
Article Abstract
Risk factors that influence the recurrence of nosocomial Clostridium difficile-associated diarrhea (CDAD) were determined in an 18-month follow-up study in a subacute geriatric department. A case-control study was conducted, comparing 43 patients with recurrent C. difficile-associated diarrhea (RCDAD) (case patients) with 38 patients who had only 1 episode of CDAD (control patients). The mean age of patients was 81.6 +/- 7.2 y (range 64-95 y). All cases with CDAD were receiving antibiotic therapy. RCDAD occurred in 53.1% of patients. Risk factors for RCDAD included fecal incontinence (p < or = 0.04), longer duration of fever from admission until first episode of CDAD (p < or = 0.02) and H2-antagonist treatment (p < or = 0.02). This study shows that RCDAD is a common clinical event in elderly hospitalized patients and may be predictable in some groups of patients.
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| http://dx.doi.org/10.1080/00365540210147525 | DOI Listing |
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