[Level of CA 125 antigen in serum of first trimester normal and miscarried pregnancy].

The ultrasound and titres of serum beta-HCG and progesterone are widely used to assess the risk of miscarriage at early stages of pregnancy. Although very useful, they are not considered as satisfactorily sensitive tests during the first three months of pregnancy. Therefore, their value is limited. Evaluation of serum levels of CA 125 antigen has been considered as useful in diagnosis and monitoring of some ovarian carcinomas. But there are some studies suggesting its predictive value when estimating the risk of miscarriage at early stages of pregnancy. The authors prove that women with threatening abortion revealed higher values of serum CA 125 antigen than those in control groups. The patients who had presented the highest values of the antigen later miscarried.