[Clinical and prognostic significance of seasonal factor in endogenous maniac states].

The study aimed at determination of clinical and prognostic significance of seasonal factor in endogenous maniac state development. Using clinico-psychopathological and clinical follow-up study, 32 patients (30 women and 2 men) aged 20-50 years with seasonal endogenous mania were examined. Seasonal mania developed in 12 patients with bipolar affective disorder, in 13 patients with schizoaffective psychosis and 7 patients with attack-like schizophrenia (F31.1 - F31.6, F25 and F20.02 + F25 ICD-10 items respectively). Seasonal maniac state was shown to be a significant clinical symptom that might be regarded as a prognostic factor. In patients with bipolar disorder--with a prevalence of both mania and depression-seasonal mania development in autumn-winter period was a favourable prognostic trait, being observed mainly in manic depressive psychosis. In spring-summer mania, prognosis was less favourable and was preferentially found in schizoaffective psychosis and attack-like schizophrenia.