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Intralesional methotrexate as non-surgical therapy for giant keratoacanthoma on the nose.
Br J Oral Maxillofac Surg
February 2024
Poole Hospital, University Hospital Dorset NHS Foundation Trust, UK.
Keratoacanthoma is an epithelial tumour derived from hair follicles. Clinical and histopathological features of keratoacanthoma can resemble that of squamous cell carcinoma. Different treatment alternatives have been described over the years including intralesional methotrexate injection.
View Article and Find Full Text PDFA Case of Pleomorphic Dermal Sarcoma: Giant Exophytic Tumor of the Medial Canthus.
Dermatopathology (Basel)
December 2023
Department of Dermatology, SSMHealth SLUCare, Saint Louis University, 1008 S Spring Ave, St. Louis, MO 63110, USA.
We present the case of a 99-year-old Caucasian female who was referred for treatment of a painless, 8.0 cm × 7.8 cm exophytic, pedunculated, ulcerated tumor of the left medial canthus.
View Article and Find Full Text PDFSurgical excision of a giant solitary keratoacanthoma in the cheek: a case report and literature review.
AME Case Rep
December 2023
Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Tianjin Medical University, Tianjin, China.
Background: Giant keratoacanthoma, a rare variant solitary of keratoacanthoma is characterized by a diameter exceeding 20 mm, rapid growth, and destruction of underlying tissue. Traditionally, it has been considered to be a self-resolving or low-grade squamous proliferation. Due to their atypical appearance, Giant keratoacanthomas may present a diagnostic challenge.
View Article and Find Full Text PDFCutaneous Verrucous Carcinomas: A Review.
J Cutan Med Surg
April 2023
117972 Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- Verrucous carcinoma (VC) is a rare, slow-growing type of squamous cell carcinoma that is mainly found in mucosal areas and has low potential for spreading to other parts of the body, although it can also occur on the skin, particularly the feet.
- The diagnosis of cutaneous verrucous carcinoma (CVC) can be complicated, as it may resemble benign conditions or more aggressive cancers, which can lead to incorrect treatment approaches.
- This review covers the characteristics of CVC, including its causes and clinicopathologic features, and provides recommendations for diagnosis and treatment, emphasizing the importance of regular follow-up examinations after treatment.
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