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The Effect of St. John's Wort Oil on Urethral Stricture: An Experimental Study in Rat Model.
Urol Res Pract
January 2025
Department of Urology, Adıyaman University, Faculty of Medicine, Adıyaman, Türkiye.
Objective: The aim was to evaluate the effect of yellow and red centaury St. John's Wort (St. JW) oil on inflammation and urethral fibrosis development in a rat urethral trauma model.
View Article and Find Full Text PDFViability and Radiosensitivity of Human Tumor Cells from Breast and Colon Are Influenced by Extract HP01.
Int J Mol Sci
January 2025
Department of Radiotherapy and Radiation Oncology, University Medical Center Rostock, Suedring 75, 18059 Rostock, Germany.
To enhance the treatment of tumors that are resistant to radio- and chemotherapy while minimizing the side effects of radiochemotherapy, researchers are continuously seeking new active compounds for use in combination with radiotherapy. Therefore, the aim of our study was to examine the cytotoxic and radiosensitizing effects of an extract from St. John's Wort (, referred to as HP01, on human epithelial tumor cells in vitro.
View Article and Find Full Text PDFThe Putative Antidiabetic Effect of on Diabetes Mellitus.
Int J Mol Sci
January 2025
Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 17 Agiou Thoma Street, 11527 Athens, Greece.
Diabetes mellitus (DM), a global disease that significantly impacts public health, has become increasingly common over time. In this review, we aim to determine the potential benefits of St. John's Wort (SJW) as an adjunct therapy for DM.
View Article and Find Full Text PDFClinical Pharmacokinetics of Fexofenadine: A Systematic Review.
Pharmaceutics
December 2024
Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60800, Pakistan.
Fexofenadine hydrochloride is a widely prescribed drug for treating histamine-mediated allergic reactions. This review systematically collates existing research on the clinical pharmacokinetics (PK) of fexofenadine, with a copious emphasis on examining the impact of stereoisomerism, disease states, and drug interactions. The search engines PubMed, Science Direct, Google Scholar, and Cochrane were scanned systematically for articles concerning the clinical PK of fexofenadine in humans.
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